Kaposi’s sarcoma (KS) is an abnormal connective tissue mass, commonly appearing as multiple lesions on the skin.
Moritz Kaposi first described the disease in the late nineteenth century. At that time it was thought to be a cancer, a hereditary condition, or a viral infection. The confusion continued at the beginning of the “AIDS epidemic” in the early 1980s, when doctors considered it the signature disease in people diagnosed with AIDS (especially in the gay community).
However, by 1994 it was established that KS is a cancer caused by a virus from the herpes family (the eighth human herpes virus), also called HHV-8 or Kaposi’s sarcoma-associated herpes virus (KSHV).