CB(1) receptor is the main cannabinoid target for an antispastic effect.
Link: Control Of Spasticity In A Multiple Sclerosis Model Is Mediated By CB1, Not CB2, Cannabinoid Receptors
Year: 2007
DOI: 10.1038/sj.bjp.0707003
Possible to probable range of efficacy of cannabis for treatment of Multiple Sclerosis (MS) according to the results found in this study.
Endocannabinoid agonists