The heart is a unique muscle that gets its own nourishment from three main vessels called the coronary arteries. In Western medicine’s model, when one or more of these coronary arteries is slowly or suddenly blocked (as in the case of a blood clot) or gradually narrows (as in the case of atherosclerosis, a build-up of plaque), the heart muscle begins to ache.
If not corrected, this “ache” can progress to tissue death called a myocardial infarction or heart attack. The size of the infarct determines survivability. In 2007, the Centers for Disease Control publicized a report identifying heart disease as the leading cause of death in the U.S., with more than 600,000 victims that year.
Rated 2.0 / 5 (How Ratings Work)
Possible to probable range of efficacy of cannabis for treatment of heart disease.
Based on 15 Studies from 2004 - 2017
Study Name, Description & Year
Rating
Cannabidiol Attenuates OGD/R-induced Damage By Enhancing Mitochondrial Bioenergetics And Modulating Glucose Metabolism Via Pentose-phosphate Pathway In Hippocampal Neurons
Laboratory Study — 2017
ENDOCANNABINOID SYSTEM: A Multi-facet Therapeutic Target
Review — 2016
Marijuana Use And Inpatient Outcomes Among Hospitalized Patients: Analysis Of The Nationwide Inpatient Sample Database
Logistic regression analysis (Correlation study), Conducted on 387,608 hospitalized patients between 2007-2011. — 2016
Cannabidiol Protects Against Doxorubicin-Induced Cardiomyopathy By Modulating Mitochondrial Function And Biogenesis
Animal study (mice) — 2015
Ligand Activation Of Cannabinoid Receptors Attenuates Hypertrophy Of Neonatal Rat Cardiomyocytes.
Laboratory Study — 2014
An Ultra-low Dose Of Tetrahydrocannabinol Provides Cardioprotection.
Animal study (mice) — 2013
Acute Administration Of Cannabidiol In Vivo Suppresses Ischaemia-induced Cardiac Arrhythmias And Reduces Infarct Size When Given At Reperfusion
Animal study (rats) — 2010
CB(2) Cannabinoid Receptor Activation Is Cardioprotective In A Mouse Model Of Ischemia/reperfusion
Animal study (mice) — 2009
5-HT (1A) Receptors Are Involved In The Cannabidiol-induced Attenuation Of Behavioural And Cardiovascular Responses To Acute Restraint Stress In Rats
Animal study (rats) — 2009
Cannabinoids And Cardiovascular Disease: The Outlook For Clinical Treatments
Meta-analysis — 2007
Cannabidiol, A Nonpsychoactive Cannabis Constituent, Protects Against Myocardial Ischemic Reperfusion Injury
Animal study (rats) — 2007
Cannabidiol, A Nonpsychoactive Cannabis Constituent, Protects Against Myocardial Ischemic Reperfusion Injury
Laboratory — 2007
The Endogenous Cardiac Cannabinoid System: A New Protective Mechanism Against Myocardial Ischemia
Animal study (rats and mice) — 2006
Delta-9-tetrahydrocannabinol Protects Cardiac Cells From Hypoxia Via CB2 Receptor Activation And Nitric Oxide Production
Laboratory Study — 2006
Cannabidiol Prevents Infarction Via The Non-CB1 Cannabinoid Receptor Mechanism
Animal study (mice) — 2004