Diabetes is a disease related to the pancreas, a relatively small gland located behind the stomach and in front of the spine that opens into the duodenum (neck of the small intestine). Of all the glands in the endocrine system, the pancreas, along with the adrenals, sits directly in the body’s center. The pancreas produces hormones such as insulin and glucagon as well as digestive enzymes that break down food into basic sugar molecules usable as food/energy by each cell of the human body.
Traditionally, orthodox medicine categorizes diabetes into three kinds: Type I, Type II, and gestational diabetes. Type I diabetes was once called juvenile diabetes because it occurred mostly in children or adolescents. In Type I, the pancreas stops producing the hormone insulin. Without insulin the body cannot use the food life depends on, cellular sugar. Treatment in the orthodox paradigm consists of daily insulin injections, normally administered by the patients themselves.
Type II diabetes, or adult-onset diabetes, is the most common form of the disease. In Type II the pancreas does not produce enough insulin, or the body’s cells are insensitive to the presence of insulin and ignore it. This prevents the body from converting sugar into energy. Early Type II usually does not require the use of insulin; modern medical practitioners generally prescribe oral pharmaceuticals instead.
Rated 2.5 / 5 (How Ratings Work)
Possible to probable range of efficacy of cannabis for treatment of diabetes mellitus.
Based on 23 Studies from 2001 - 2017
Study Name, Description & Year
Rating
Targeting Cannabinoid Signaling In The Immune System: “High”-ly Exciting Questions, Possibilities, And Challenges
Review — 2017
Efficacy And Safety Of Cannabidiol And Tetrahydrocannabivarin On Glycemic And Lipid Parameters In Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Pilot Study
A randomized, double-blind, placebo-controlled study, conducted on 62 patients with noninsulin-treated type 2 diabetes — 2016
Experimental Cannabidiol Treatment Reduces Early Pancreatic Inflammation In Type 1 Diabetes
Animal study — 2016
Cannabis Smoking And Diabetes Mellitus: Results From Meta-analysis With Eight Independent Replication Samples
Meta-analysis — 2015
Efficacy Of Inhaled Cannabis On Painful Diabetic Neuropathy.
A randomized, double-blinded, placebo controlled crossover study was conducted in 16 patients with painful diabetic peripheral neuropathy — 2015
Cannabis Use In Relation To Obesity And Insulin Resistance In The Inuit Population
Survey conducted on 786 Inuit — 2015
Fetal Endocannabinoids Orchestrate The Organization Of Pancreatic Islet Microarchitecture
Animal study (mice) — 2015
A Role For Trans-caryophyllene (TS) In The Moderation Of Insulin Secretion.
Laboratory test — 2014
The Impact Of Marijuana Use On Glucose, Insulin, And Insulin Resistance Among US Adults
Survey of 4657 adult men and women. 579 were current marijuana users and 1975 were past users. — 2013
The Cannabinoid Δ(9)-tetrahydrocannabivarin (THCV) Ameliorates Insulin Sensitivity In Two Mouse Models Of Obesity
Animal study (mice) — 2013
CB1 Cannabinoid Receptors Couple To Focal Adhesion Kinase To Control Insulin Release
Laboratory Study — 2013
Decreased Prevalence Of Diabetes In Marijuana Users: Cross-sectional Data From The National Health And Nutrition Examination Survey (NHANES) III
Cross-sectional study — 2012
Cannabidiol As An Emergent Therapeutic Strategy For Lessening The Impact Of Inflammation On Oxidative Stress
Review — 2011
Cannabidiol Attenuates Cardiac Dysfunction, Oxidative Stress, Fibrosis, And Inflammatory And Cell Death Signaling Pathways In Diabetic Cardiomyopathy
Animal study (mice) — 2010
Cannabinoid CB(1) Receptor Activation Stimulates Neurite Outgrowth And Inhibits Capsaicin-induced Ca(2+) Influx In An In Vitro Model Of Diabetic Neuropathy
Laboratory — 2009
Effect Of Cannabinoid Receptor Agonists On Streptozotocin-induced Hyperalgesia In Diabetic Neuropathy
Animal study (mice) — 2008
Cannabidiol Arrests Onset Of Autoimmune Diabetes In NOD Mice
Animal study (mice) — 2008
Cannabidiol Lowers Incidence Of Diabetes In Non-obese Diabetic Mice
Animal study (mice) — 2006
Neuroprotective And Blood-retinal Barrier-preserving Effects Of Cannabidiol In Experimental Diabetes
Animal study (rats) — 2006
Cannabinoids Blocks Tactile Allodynia In Diabetic Mice Without Attenuation Of Its Antinociceptive Effect
Animal study (mice) — 2004
The Effect Of WIN 55,212-2, A Cannabinoid Agonist, On Tactile Allodynia In Diabetic Rats
Animal study (rats) — 2004
Examination Of The Immunosuppressive Effect Of Delta9-tetrahydrocannabinol In Streptozotocin-induced Autoimmune Diabetes
Animal study (mice) — 2001